number,recommendation,type,strength,certainty
1.2,Benzoyl peroxide,Graded recommendation,Strong,Moderate
1.3,Topical retinoids,Graded recommendation,Strong,Moderate
1.4,Topical antibiotics,Graded recommendation,Strong,Moderate
1.5,Clascoterone,Graded recommendation,Conditional,High
1.6,Salicylic acid,Graded recommendation,Conditional,Low
1.7,Azelaic acid,Graded recommendation,Conditional,Moderate
1.8,Fixed-dose topical antibiotic + benzoyl peroxide,Graded recommendation,Strong,Moderate
1.9,Fixed-dose topical retinoid + antibiotic,Graded recommendation,Strong,Moderate
1.10,Fixed-dose topical retinoid + benzoyl peroxide,Graded recommendation,Strong,Moderate
2.1,Doxycycline (systemic),Graded recommendation,Strong,Moderate
2.2,Minocycline (systemic),Graded recommendation,Conditional,Moderate
2.3,Sarecycline (systemic),Graded recommendation,Conditional,High
2.4,Doxycycline in preference to azithromycin,Graded recommendation,Conditional,Low
3.1,Combined oral contraceptive pills,Graded recommendation,Conditional,Moderate
3.2,Spironolactone,Graded recommendation,Conditional,Moderate
4.2,Traditional daily isotretinoin over intermittent dosing,Graded recommendation,Conditional,Low
4.3,Standard or lidose isotretinoin (equivalent options),Graded recommendation,Conditional,High
5.1,Pneumatic broadband light added to adapalene 0.3% gel,Graded recommendation,Conditional against,Low
1.1,"Multimodal topical therapy, combining mechanisms of action",Good practice statement,Ungraded,Not graded
2.5,Limiting the duration of systemic antibiotic use,Good practice statement,Ungraded,Not graded
2.6,Concomitant benzoyl peroxide with systemic antibiotics,Good practice statement,Ungraded,Not graded
3.3,Intralesional corticosteroid injection for individual lesions,Good practice statement,Ungraded,Not graded
4.1,Isotretinoin for severe acne,Good practice statement,Ungraded,Not graded